Research Progress in Dipeptidyl Peptidase-4 Inhibitors
- VernacularTitle:二肽基肽酶-4抑制药研究进展
- Author:
Feng CAO
;
Fangjian WU
- Publication Type:Journal Article
- Keywords:
DPP-4 inhibitors;
Type 2 diabetes mellitus;
Research progress
- From:
China Pharmacist
2014;(4):667-670
- CountryChina
- Language:Chinese
-
Abstract:
Dipeptidyl peptidase-4 (DPP-4) inhibitors, a new kind of oral hypoglycemic drugs, can significantly lower blood glu-cose levels in the patients with type 2 diabetes without common side effects such as body weight gain, hypoglycemia and gastrointestinal disturbances. Therefore, DPP-4 inhibitors play an increasingly important role in the treatment of type 2 diabetes. In this review, the re-search progress in the action mechanism, pharmacokinetics and clinical applications of DPP-4 inhibitors was summarized in order to provide reference for the clinical application.
