Optimization of Extraction Process of Kanglao Qingfei Granules by Orthogonal Test with Multi-indexes
10.3969/j.issn.1005-5304.2014.05.028
- VernacularTitle:多指标正交试验优选抗痨清肺颗粒提取工艺
- Author:
Chunqing LUO
;
Xinhua XIA
;
Xiping TAN
;
Maijiao PENG
;
Jianguo ZENG
;
Yanke LIU
- Publication Type:Journal Article
- Keywords:
Kanglao Qingfei granules;
orthogonal test;
extraction technology;
bergenin;
polysaccharide
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2014;(5):91-94
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the extraction process of Kanglao Qingfei granules. Methods Orthogonal test design was used to study the influence of soaking time, water content, extraction time on extraction technology with bergenin's extraction rate, total polysaccharides's extraction rate and extract yield as evaluation indexes. Results The optimum extraction process conditions were as follows:the raw materials were immersed in water for 1.0 h and extracted two times under reflux, and the ratio of water volume to raw materials weight was 10 and 8 (mL/g), and extraction time was 2.5 h and 2.0 h, respectively. Conclusion The optimized extraction process was simple and stable, which can provide foundation for industrial production of Kanglao Qingfei granules.
