Prognostic factors for diabetic foot ulcer
10.3760/cma.j.issn.1001-8050.2014.04.002
- VernacularTitle:糖尿病足溃疡预后相关因素研究
- Author:
Chuanbo LIU
;
Yao HUANG
;
Junna YE
;
Pengwen NI
;
Shuliang LU
- Publication Type:Journal Article
- Keywords:
Diabetic foot;
Prognosis;
Prospective studies
- From:
Chinese Journal of Trauma
2014;30(4):291-297
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the factors related to prognosis of diabetic foot ulcer (DFU).Methods A total of 186 patients with type Ⅱ DFU from a single diabetic foot center was included in this prospective study.Follow-up of the final outcome (healing,major amputation or death) was made in 6 months.Influence of patient demographics and clinical data on outcome was detected using multivariate Logistic regression analysis.Results Follow-up was performed in 172 patients,of whom 147 were cured (55 cases cured after minor amputations),3 underwent major amputations,6 died,and 16 were not yet cured at the final follow-up.In multivariate Logistic regression analysis,the outcome was independently correlated with ischemia (P <0.01),infection (P < 0.05),ulcer number (P < 0.01) and peripheral neuropathy (P < 0.05) ; the risk of poor outcome increased with ischemia [odds ratio (OR) =10.8],infection (OR =211.4),ulcer number (OR =39.5),and peripheral neuropathy (OR =181.1).Conclusion Prognosis of DFU is associated with ischemia,infection,ulcer number,and peripheral neuropathy.