Investigation of the value in clinical diagnosis of two dimers (D-D), fibrinogen (Fbg) and platelet parameters (PLT, MPV, PDW) level induced by postoperative deep vein thrombosis (DVT) in patients with severe trauma
- VernacularTitle:D-二聚体、纤维蛋白原等指标检测在严重创伤患者术后形成深静脉血栓中的临床价值
- Author:
Guohua FANG
;
Ping LI
- Publication Type:Journal Article
- Keywords:
Severe trauma patients;
With D-two dimer;
Fibrinogen;
Platelet index;
Of deep vein thrombosis
- From:
Journal of Chinese Physician
2013;(z1):11-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the D-in patients with severe trauma in two dimers (D-D),fibrinogen (Fbg) and platelet parameters (PLT,MPV,PDW) level induced by postoperative deep vein thrombosis (DVT) in the formation of value in clinical diagnosis.Methods Eighty cases of healthy people as control group,were compared before and after operation and level and 321 severe traumatic patients were measured before surgery,after 1 days and 3 days of D-D,Fbg and platelet parameters,trauma were divided into fracture,traumatic brain injury,multiple injuries in three groups.Results Different trauma patients with D-D,Fbg concentration and platelet index compared with the control group increased obviously significant (P ＜ 0.05),especially the brain trauma and multiple injuries in two group increased significantly (P ＜0.01),the positive rate of D-D was 22.8％,35.2％,40.9％.Postoperative 1D in addition to brain injury group,trauma group D-D levels compared with those before operation were significantly increased with significant (P ＜ 0.05),other indicators compared with preoperative changes little,the positive rate of D-D increased slightly,but without statistical significance.Levels of Fbg 3D after the trauma group decreased significantly,D-D increased significantly,decreased the number of PLT,MPV,PDW value increases,the value of preoperative has the remarkable significance (P ＜ 0.01 or P ＜ 0.05).The positive rate of D-D was increased up to 41％,59.2％,62.3％,compared with those before operation by chi-square test was significant (P ＜0.01).Conclusion The patients with severe trauma patients after two D-dimer concentration should be alert to the occurrence of DVT,contribute to the clinically as soon as possible to take measures to avoid,there is an important clinical significance in the treatment and prognosis of trauma patients.
