Biological motion perception in patients with Parkinson's disease

VernacularTitle:帕金森病患者生物运动感知能力研究
Author: Ruihua CAO ; Xing YE ; Yanghua TIAN ; Panpan HU ; Xianwen CHEN ; Kai WANG
Publication Type:Journal Article
Keywords: Parkinson's disease; Biological motion; Cognition; Mirror neuron system
From: Chinese Journal of Behavioral Medicine and Brain Science 2014;23(3):193-195
CountryChina
Language:Chinese
Abstract: Objective To explore the biological motion perception in Parkinson's disease (PD).Methods 45 individuals with idiopathic PD were compared with 45 matched healthy controls (HCs) using a duration discrimination task.Results The point of subjective equality(PSE) was negative value (-0.27±0.17) for health controls (HCs),and there was significant difference compared with PSE =0 by one sample t test (t=10.96,P＜ 0.01).Compared with HCs,the PSE for PD patients (-0.14±0.30) significantly decreased (t=2.63,P=0.01).When further dividing PD into early stages (stage 1-2) and late stages (stage 3-4),significant difference was found between late-stage PD patients(0.02±0.39)and HCs (t=4.07,P=0.008),but not between early-stage PD patients (-0.24±0.14) and HCs (t=0.84,P=0.405).Conclusion There is biological motion perception disorder in PD patients and it is related to the severity of PD.