The effectiveness of integrative therapy on serum IL-8 and IL-17 in patients with chronic urticaria

VernacularTitle:中西医结合治疗对慢性荨麻疹患者血清IL-8和IL-17的影响
Author: Cunzhu CUI
Publication Type:Journal Article
Keywords: Urticaria; Traditional chinese medicine; Interleukin
From: Chinese Journal of Primary Medicine and Pharmacy 2014;21(8):1164-1166
CountryChina
Language:Chinese
Abstract: Objective To study the effectiveness of integrative therapy on serum IL-8 and IL-17 in patients with chronic urticaria.Methods According to the digital table,126 patients with chronic urticaria were randomly divided into the two groups,the control group (n =63 cases) and the observation group (n =63 cases).The patients in the control group were treated through cetirizine hydrochloride and ebastine,while the patients in the observation group were treated through cetirizine hydrochloride and ebastine plus traditional chinese medicine.They were treated for 4 weeks.Serum IL-8 and IL-17 were detected before and after treatment.Results The effective rates were 77.8％ in control group and 9 5.2 ％ in the observation group with a significant difference between the two groups (x2 =4.78,P ＜ 0.05).Serum IL-8 and IL-17 in two groups were significantly reduced,and after treatment,the observation group decreased more significantly(t =2.92,3.06,both P ＜ 0.05).Conclusion Integrative therapy can significantly decrease serum IL-8 and IL-17 in patients with chronic urticaria.