Effect of assisted thoracic small incision on serum CK19 mRNA and Lunx mRNA in patients with lung cancer
10.3760/cma.j.issn.1008-6706.2014.06.036
- VernacularTitle:胸腔镜辅助小切口手术治疗肺癌对患者血清CK19mRNA和LunxmRNA的影响
- Author:
Dongtao WANG
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Thoracoscopy;
CK19 mRNA;
Lunx mRNA
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;21(6):880-881
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of assisted thoracic small incision on serum CK19 mRNA and Lunx mRNA in patients with lung cancer.Methods 90 patients with lung cancer were randomly divided into the control group and the observation group.45 patients in the control group were operated through thoracotomy,while 45patients in the observation group were operated through assisted thoracic small incision.Serum CK19 mRNA and Lunx mRNA were detected before and after operation through RT-PCR.Results Serum CK19 mRNA and Lunx mRNA were decreased after operation (t =19.682,12.784,7.824,7.085,all P ＜ 0.01).And the mRNA levels in the observation group were lower than those in the control group (t =1.900,1.438,all P ＜ 0.05).Conclusion Assisted thoracic small incision can decrease serum CK19 mRNA and Lunx mRNA in patients with lung cancer,which can improve micrometastasis.
