Influence of Qiangxin Tongmai decotion on heart function and plasma brain natriuretic peptide level in patients with chronic heart failure

VernacularTitle:强心通脉汤对慢性心力衰竭患者心功能及血浆脑钠肽水平的影响
Author: Dong LIN ; Zhi SHANG
Publication Type:Journal Article
Keywords: Heart failure,congestive; Heart function tests; Natriuretic peptide,brain; Qiangxin Tongmai decotion
From: Chinese Journal of Primary Medicine and Pharmacy 2014;21(6):868-869
CountryChina
Language:Chinese
Abstract: Objective To explore the effect of conventional western medicine combined with Qiangxin Tongmai decotion in the treatment of patients with chronic heart failure (CHF).Methods According to the digital table,60 patients with CHF were randomly divided into two groups,30 cases in each group.The control group was treated with conventional western medicine,while the treatment group received combination therapy of conventional western medicine and Qiangxin Tongmai decotion.The heart function and plasma brain natriuretic peptide (BNP) level were observed.Results The total effective rate of the treatment group was 93.3％,which was significantly higher than 70.0％ of the control group (x2 =5.455,P ＜ 0.05).After treatment,the level of BNP in the treatment group was (211.3 ± 87.7) ng/L,which was significantly lower than that of the control group [(410.8 ± 94.3) ng/L] (t =8.485,P ＜ 0.01).Conclusion Qiangxin Tongmai decotion can obviously improve the heart function and reduce the level of BNP in patients with CHF.