Research progress of uncoupling protein 2 in pathophysiology of sepsis
10.3760/cma.j.issn.2095-428X.2014.06.018
- VernacularTitle:解偶联蛋白2参与脓毒症病理生理机制的研究进展
- Author:
Zhijiang CHEN
;
Yuanbin SONG
;
Yang WANG
;
Dong CHEN
;
Di CHE
;
Qiyi ZENG
- Publication Type:Journal Article
- Keywords:
Sepsis;
Uncoupling protein 2;
Pathophysiology;
Mitochondria;
Research progress
- From:
Chinese Journal of Applied Clinical Pediatrics
2014;29(6):464-466
- CountryChina
- Language:Chinese
-
Abstract:
Uncoupling protein 2 (UCP2) is a proton transporter which presents in the mitochondrial inner membrane.Recently studies found that UCP2 plays important roles in regulation of reactive oxygen species production,maintenance of mitochondrial function,as well as inflammation and blood glucose control.These features have important relevance with the pathophysiologic mechanism of sepsis.
