Relationship of genetic and environmental factors on obesity in children
10.3760/cma.j.issn.2095-428X.2014.08.003
- VernacularTitle:儿童肥胖的遗传背景及与环境因素的关系
- Author:
Chunlin WANG
;
Li LIANG
- Publication Type:Journal Article
- Keywords:
Obesity;
Gene;
Epigenetics;
Environment;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2014;29(8):568-570
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis of obesity in children is unclear.Genetic play an important role,including gene mutations,polymorphisms,epigenetics.And the other hand,environment factors such as intrauterine environment,nutrition,physical exercise,and gut microflora also affect the obesity.The genetic and environment factors have interaction,leading to the occurrence of childhood obesity and development.With the advances in molecular biology techniques and large-scale,large sample size of population screening,new obesity-related genes,single nucleotide polymorphisms,the apparent genetic markers will continue to be found,looking forward to the future predict obesity,to choose to guide effective treatment,or even contribute to the development of genetic targeting drugs.
