Roles of connexin in breast cancer
10.3760/cma.j.issn.1673-422X.2014.04.011
- VernacularTitle:细胞间隙连接蛋白在乳腺癌中的作用
- Author:
Chen XIA
;
Zhigang ZHUANG
- Publication Type:Journal Article
- Keywords:
Connexins;
Breast neoplasms;
Neoplasm metastasis;
Antineoplastic protocols
- From:
Journal of International Oncology
2014;41(4):273-276
- CountryChina
- Language:Chinese
-
Abstract:
The previous studies identify connexin as a tumor suppressor gene,which inhibits the occurrence and development of breast cancer.However,some researches of resent years demonstrate that the expression level of connexin in a large part of metastatic breast cancer is elevated and connexin may promote breast cancer metastasis.Therefore,connexin may play different roles by different mechanisms in the occurrence,development,invasion and metastasis of breast cancer.Rational use of connexin in breast cancer treatment can be beneficial to breast cancer patients.
