Anti-tumor mechanisms of plant alkaloids
10.3760/cma.j.issn.1673-422X.2014.04.005
- VernacularTitle:植物生物碱的抗肿瘤机制
- Author:
Xiaowei FENG
;
Xudong TANG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Alkaloid;
Mechanism
- From:
Journal of International Oncology
2014;41(4):254-258
- CountryChina
- Language:Chinese
-
Abstract:
Plant alkaloids have anti-tumor activities.In recent years,the anti-tumor mechanisms of plant alkaloid are demonstrated to be related to the block of tumor cell cycle,the induction of tumor cell apoptosis,the inhibition of tumor angiogenesis and multi-drug resistance.In addition,most recently,plant alkaloids are found to inhibit telomerase activity and induce autophagy.Therefore,plant alkaloids may be developed into a sort of potential antitumor drugs.
