Roles and resistance mechanisms of survivin in tumor
10.3760/cma.j.issn.1673-422X.2014.04.001
- VernacularTitle:生存素在肿瘤中的作用及其耐药机制
- Author:
Ying ZHENG
;
Qin CHEN
;
Bin ZHANG
;
Xuchen CAO
- Publication Type:Journal Article
- Keywords:
Drug resistance,neoplasm;
Neoplasms;
Multidrug resistance-associated proteins;
Survivin
- From:
Journal of International Oncology
2014;41(4):241-244
- CountryChina
- Language:Chinese
-
Abstract:
Drug resistance in tumor treatment is an important factor that affects disease outcome.A lot of researches show that survivin can inhibit tumor cell apoptosis,regulate cell cycle,promote angiogenesis and tumor metastasis.The interactions among survivin,genes and proteins can influence the drug resistance of tumor cells.
