Effect of carotid artery stenting on cognitive function in patients with asymptomatic severe carotid artery stenosis
10.3760/cma.j.issn.1673-4165.2014.03.003
- VernacularTitle:颈动脉支架置入术对无症状重度颈动脉狭窄患者认知功能的影响
- Author:
Qiyuan ZHAO
;
Ping JIN
;
Zhangsong WU
;
Jun ZHANG
;
Sheng CHEN
;
Kai WANG
- Publication Type:Journal Article
- Keywords:
Carotid Stenosis;
Angioplasty;
Stents;
Cognition;
Cognition Disorders;
Time Factors
- From:
International Journal of Cerebrovascular Diseases
2014;22(3):172-175
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of carotid artery stenting (CAS) on cognitive function in patients with asymptomatic severe carotid artery stenosis.Methods The patients with asymptomatic severe carotid stenosis (stenosis ≥ 70％) were enrolled in the study.The cognitive function evaluation was performed before CAS,1 and 3 months after procedure respectively with mini-mental status scale (MMSE),digital span (DS),Chinese auditory learning test (CALT),judgment of line orientation test (JLOT),and verbal fluency test (VFT),including attention,memory,visual spatial function,and frontal fluency function.Results A total of 26 patients with asymptomatic severe carotid artery stenosis who performed CAS were enrolled,18 were males and 8 were females (aged 52 to 79 years,mean 64.19 ±6.76 years),and the years of education was 9.84 ± 3.29 years.Eighteen patients had left carotid artery stenosis and 8 had contralateral carotid artery stenosis.CAS was performed successfully in all patients,and no complications occurred.Compared with the CAS before procedure,all the cognitive functions were improved significantly at 1 and 3 months after procedure (all P ＜0.01),however,there was no significant difference between 1 and 3 months after procedure (all P＞ 0.05).Conclusions CAS may improve cognitive function in patients with asymptomatic severe carotid artery stenosis,and it was more obvious in the early postoperative period.
