Molecular imaging of cerebral ischemic penumbra
10.3760/cma.j.issn.1673-4165.2014.02.006
- VernacularTitle:脑缺血半暗带的分子影像学
- Author:
Jinping WAN
;
Min LOU
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain Ischemia;
Molecular Imaging;
Magnetic Resonance Imaging;
Positron-Emission Tomography;
Tomography,Emission-Computed,Single-Photon;
Electron Spin Resonance Spectroscopy;
Magnetic Resonance Spectroscopy
- From:
International Journal of Cerebrovascular Diseases
2014;22(2):116-121
- CountryChina
- Language:Chinese
-
Abstract:
Molecular imaging develops faster in the field of neuroimaging of ischemic stroke.Many studies have shown that its values in the aspects of cerebral blood flow monitoring during ischemic stroke and brain tissue metabolism.Ischemic penumbra is the basis of reperfusion therapy for acute ischemic stroke.The imaging methods,including magnetic resonance perfusion-weighted imaging/diffusion-weighted imaging mismatch,have been widely used to reveal ischemic penumbra because of their fast and strong availability.However,they can only reveal the blood flow of penumbra tissue.By contrast,molecular imaging technology can describe and measure the in vivo biological processes on the cellular and molecular levels,thus it can more accurately reveal the penumbral tissue.