The new generation drug- eluting stents and their effects of anti- thrombosis
10.3969/j.issn.1008-794X.2014.05.001
- VernacularTitle:新一代药物洗脱支架及其抗血栓形成的作用
- Author:
Yong OUYANG
;
Xuehui OUYANG
;
Xuejun ZHANG
;
Zhiyong WANG
- Publication Type:Journal Article
- Keywords:
percutaneous coronary intervention;
drug - eluting stent;
nanomaterial and nanotechnology;
biodegradable drug-eluting stent;
in-stent thrombosis
- From:
Journal of Interventional Radiology
2014;(5):369-375
- CountryChina
- Language:Chinese
-
Abstract:
This paper aims to make a comprehensive review about the new generation drug-eluting stents and their effects of anti-thrombosis to decrease stent thrombosis (ST), which are very helpful for interventional radiologists, especially for cardiologists who are engaged in percutaneous coronary interventional therapy. Based on the review of recently published academic papers and the investigation of the manufacturers and market of stent, the main factors related to ST complication which is associated with new generation drug-eluting stents are retrospectively and briefly analyzed. Besides, a variety of new generation drug-eluting stents with anti-thrombosis effect that are being successfully developed recently with new technology and new materials, including the renewal or improvement of the stent platform, loaded drug, carrier and its loading technology, etc. are comprehensively described in this paper in a combination way of vivid pictures with corresponding essay. In addition, the development and the prospect in clinical application of biodegradable drug-eluting stents are also briefly discussed in this paper.