Clinical application of percutaneous vertebroplasty in treating osteoblastic spinal metastases
10.3969/j.issn.1008-794X.2014.05.010
- VernacularTitle:经皮椎体成形术治疗成骨性脊柱转移癌的临床应用
- Author:
Qinghua TIAN
;
Chungen WU
;
Yifeng GU
;
Tao WANG
;
Yv HE
;
Hongmei SONG
;
Fei YI
;
Chengjian HE
;
Quanping XIAO
;
Yongde CHENG
- Publication Type:Journal Article
- Keywords:
percutaneous vertebroplasty;
spine;
osteoblastic metastasis
- From:
Journal of Interventional Radiology
2014;(5):411-414
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the feasibility and short-term clinical effectiveness of DSA-guided percutaneous vertebroplasty (PVP) for the treatment of painful osteoblastic metastatic spinal lesions. Methods During the period from Jan. 2010 to Dec. 2011 at authors’ hospital PVP was carried out in 23 patients with osteoblastic spinal metastases (34 lesions in total). Coexisting osteoblastic pathological fracture was found in twelve patients. The WHO standards, visual analogue scale (VAS) and karnofsky-KPS score were used to evaluate the therapeutic results. Results Technical success was achieved in all patients. All patients were followed up for at least 3 months. Of 20 patients who had complete clinical data, complete remission (CR) was obtained in 6, partial remission (PR) in 10, mild remission (MR) in 3 and no remission (NR) in one. The clinical effectiveness (CR+PR) was 80%. The mean VAS scores dropped from preoperative (7.0 ± 1.6) to (2.2 ± 1.9) at 24 hours after the treatment, and to (2.4 ± 2.1) and (2.5 ± 2.1) at one and three months after the treatment respectively. The mean KPS scores rose from preoperative (76.5 ± 10.4) to (86.5 ± 11.8), (88.0 ± 12.0) and (89.0 ± 10.8) at 24 hours and one, three months after the treatment respectively. Small amount leakage of PMMA was observed in 4 cases (17.4%) with no obvious clinical symptoms. Conclusion DSA-guided PVP is a feasible and effective treatment for painful osteoblastic spinal metastases. This therapy can immediately relieve pain and reinforce spine, besides, it can remarkably improve the living quality and
decrease the incidence of paraplegia.
