Progression of adjuvant radiotherapy upon breast cancer immunity
10.3969/j.issn.1007-3969.2014.05.012
- VernacularTitle:乳腺癌辅助放疗对抗肿瘤免疫影响的研究进展
- Author:
Xiaofang WANG
;
Xiaomao GUO
- Publication Type:Journal Article
- Keywords:
Breast cancer;
Radiotherapy;
Immunity
- From:
China Oncology
2014;(5):392-396
- CountryChina
- Language:Chinese
-
Abstract:
Immunity is the basic defense barrier for body, and also closely related to the development, progression, treatment and prognosis of breast cancer. Adjuvant radiotherapy plays an important role in the multidisciplinary treatment of breast cancer. It has long been believed that radiotherapy was immunosuppressive because it could destroy the body’s immune cells directly. While recent studies have shown that radiotherapy can stimulate the host immune system in the antitumor process, including antigen processing, presentation, recognition, and eventually tumor-cell killing. In the clinical aspect, a variety of immune targeted therapies, combined with radiotherapy, have entered clinical trials. The article reviewed research progress and status of the inlfuence of breast cancer adjuvant radiotherapy on antitumor immunity.
