Clinical study of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection aided identiifcation and treatment of ischemic stroke
- VernacularTitle:丹参川芎嗪注射液辅助辨治缺血性脑卒中的临床研究
- Author:
Wenkai LIU
;
Huiliang XIAO
;
Xuzhou ZHOU
- Publication Type:Journal Article
- Keywords:
salviae miltiorrhizae and ligustrazine hydrochloride injection;
ischemic stroke;
clinical study
- From:
Chinese Journal of Biochemical Pharmaceutics
2014;(2):110-111
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection in inauxiliary treatment of ischemic stroke and its clinical efficacy. Methods 142 cases of patients with ischemic stroke, were randomly divided into experimental group and control group. Control group(n=71) were treated with conventional therapy. Test group(n=71) were treated with Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection on the basis of conventional therapy. Hemorheological changes, nerve function improvement and treatment efifcacy in two groups before and after treatment were observed and analyzed. Results After treatment, the plasma viscosity and hematocrit in control group were 1.91±0.35, (49.58±1.04)%; while experimental group were 1.17±0.28, (38.97±1.31)%, the differences between two groups were signiifcant(P<0.05). Before treatment, the neurological function score in control group was 22.49±1.21, while experimental group was 23.18±1.74, there was no signiifcant difference between two groups. After treatment, the neurological function score in control group was 10.58±0.94, while experimental group was 4.62±2.05, the difference was signiifcant(P<0.05). The total effective rate was 80.3%in control group ,while 88.7% in experimental group, the difference was signiifcant(P<0.05). Conclusion The clinical efifcacy of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection in auxiliary treatment of ischemic stroke was accurate, and it can alleviate the symptom of patients.
