The express and research of chemerin and CRP in 45 patients with early-onset preeclampsia
10.3969/j.issn.1671-8348.2014.15.012
- VernacularTitle:45例早发型子痫前期患者血清chemerin、CRP的变化及其意义
- Author:
Xiaodong LUO
;
Xiaojing DONG
;
Jin ZHOU
;
Jiangchuan SUN
- Publication Type:Journal Article
- Keywords:
C-reactive protein;
early-onset preeclampsia;
chemerin
- From:
Chongqing Medicine
2014;(15):1857-1859
- CountryChina
- Language:Chinese
-
Abstract:
Objective The purpose of this study was to compare chemerin and CRP levels between women with and without ear‐ly‐onset preeclampsia based on maternal body mass index (BMI) .Methods 45 patients with early onset preeclampsia (gestation week is less than 34 weeks) ,30 normal pregnancy women were enrolled in the study .The serums levels of chemerin and CRP were measured in these pregnancy women .Results The chemerin [(379 .18 ± 52 .09)ng/L ,(481 .27 ± 63 .12)ng/L] and CRP [(7 .59 ± 1 .41)mg/L ,(11 .74 ± 1 .61)mg/L] levels in MPE and SPE were significantly higher than those [(316 .08 ± 51 .90)ng/L ,(3 .47 ± 1 .27)mg/L]in normal pregnancy women(P<0 .05) .While the chemerin(424 .64 ± 46 .61)ng/L and CRP (8 .32 ± 3 .82)mg/L levels increased with maternal BMI in patients overweight and obese women levels compared with normal weight women [(331 .66 ± 51 .77)ng/L ,(5 .93 ± 2 .95)mg/L] ,the difference are significant(P<0 .05) .The correlation analysis showed that the chemerin were positively correlated with BMI ,systolic blood pressure ,diastolic blood pressure ,triglycerides ,and CRP were positively correlated with BMI .Conclusion The expression of chemerin and CRP were associated with severity of preeclampsia and BMI .
