Expression and significance of IL-4 and IL-10 in anaphylactic shock
10.3969/j.issn.1671-8348.2014.15.026
- VernacularTitle:I L-4与I L-10在过敏性休克中的表达及意义
- Author:
Hang LI
;
Jian YU
- Publication Type:Journal Article
- Keywords:
guinea pig;
anaphylactic shock;
interleukin-4;
interleukin-10
- From:
Chongqing Medicine
2014;(15):1898-1900
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish animal model of guinea pig anaphylactic shock ,explore the expression of IL‐4 and IL‐10 in guinea pig serum ,provide scientific and objective evidence for medicolegal and clinical diagnosis of anaphylactic shock as well .Meth‐ods After 40 guinea pigs were classified into the experimental and the control groups ,in which the experimental group was 30 and the control group was 10 ,Elisa method was used to detect IL‐4 and IL‐10 by extracting serum of guinea pigs in the experiment group and the control group .Results The IL‐4 levels of serum in experimental group was higher than that in control group (P<0 .01);the IL‐10 levels of serum in experimental group was higher than that in control group (P<0 .01) .Conclusion The level of serum IL‐4 and IL‐10 in the experiment group are obviously higher than that of the control group .This provides an evidence for an‐aphylactic shock forensic identification and clinical diagnosis .
