Effectiveness evaluation of personalized medication for cardiovascular drugs based on the CYP2 C9 protein
10.7644/j.issn.1674-9960.2014.04.015
- VernacularTitle:基于CYP2 C9靶蛋白的心血管药物个体化用药效能评价
- Author:
Yuefeng TONG
;
Shuai YANG
;
Zhixing HU
;
Yunxiang WANG
;
Changchun LAI
;
Zhecheng LI
;
Qin SU
- Publication Type:Journal Article
- Keywords:
CYP2C9;
cardiovascular drugs;
effectiveness evaluation;
multi-layer fuzzy evaluation
- From:
Military Medical Sciences
2014;(4):294-297
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the effectiveness evaluation of cardiovascular drugs which have been developed on the CYP2C9 target protein by multi-layer fuzzy evaluation technology .Methods The multi-layer fuzzy evaluation method was used to evaluate the effectiveness of cardiovascular drugs interacting with the CYP 2C9 protein and to construct the index system that affects drug efficacy .Results and Conclusion The index system was used to study such cardiovascular drugs as valsartan and to score the drug effectiveness of individual samples .The results were consistent with actual drug treatment and were well confirmed .The results contribute to evaluation of personalized medication .