Evaluation on a modified Ziehl-Neelsen stainin the diagnosis of tuberculous meningitis
10.3936/j.issn.1002-0152.2014.03.005
- VernacularTitle:改良抗酸染色法在结核性脑膜炎诊断中的应用
- Author:
Yueli ZOU
;
Ge BAI
;
Hui PU
;
Beilei WANG
;
Yanan TIAN
;
Lihua QIAN
;
Sha WANG
;
Junying HE
- Publication Type:Journal Article
- Keywords:
Tuberculous meningitis;
Modified Ziehl-Neelsen stain;
Cerebrospinal fluid
- From:
Chinese Journal of Nervous and Mental Diseases
2014;(3):149-152
- CountryChina
- Language:Chinese
-
Abstract:
Objective Toevaluatea modified Ziehl-Neelsen(Z-N) stain in the diagnosis of tuberculous meningitis. Methods Cerebrospinal fluid specimens from 35 patients were stained by using the modified Ziehl-Neelsen staining. Re-sults The positive rate was 94.29% in 35 patients with tuberculous meningitisand the intracellular acid-fast bacilli was detected in 53.40%of all specimens. One case was stained positive in 15 patients with non-tuberculous meningitis. Con-clusion The modified Ziehl-Neelsen stain not only significantly improves the detection rates of tuberculous meningitisbut alsois able to identify intracellular M.tuberculosisin cerebrospinal fluidspecimen.Thus, the modified Z-N stain can be a convenient tool for diagnosing tuberculous meningitis.
