The clinical observation of mannatide treatment with burn infection
- VernacularTitle:甘露聚糖肽治疗烧伤感染的临床疗效观察
- Author:
Hongyan LIU
;
Wenlian HUANG
;
Wenming XIAO
- Publication Type:Journal Article
- Keywords:
burn;
mannatide;
immune function
- From:
Chinese Journal of Biochemical Pharmaceutics
2014;(2):133-134
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effect of mannatide treatment with burn infection. Methods 100 burn patients admitted to Sichuan Nanchong Central Hospital from May 2009 to July 2012 were randomly divided into control group and treatment group, each group had 50 cases. Both of two groups were given conventional treatment, treatment group were treated with intravenous mannatide,control group were injected recombinant human growth hormone. Results The average length of stay in treatment group was signiifcantly shorter than control group (P=0.042). The clinical total effective rate, serum IgA, IgG, IgM and other indicators of immune function were improved signiifcantly compared with control group (P=0.037). There was no statistical signiifcance in blood protein, transferrin, prealbumin, glucose, insulin, urinary sodium, urinary potassium, chloride and other indicators of patients between two groups. Conclusion Mannatide can effectively enhance immune function, promote wound healing, shorter hospital stay and improve the clinical efifcacy.
