Clinical analysis of proton pump inhibitor combined with Clostridium butyricum live bacteria tablets on treatment with HP type peptic ulcer patients
- VernacularTitle:HP型消化性溃疡患者应用质子泵抑制剂和梭菌酪酸活菌片进行治疗的临床分析
- Author:
Wenbin YANG
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
peptic ulcer;
proton pump inhibitor;
clostridium butyricum living bacterium
- From:
Chinese Journal of Biochemical Pharmaceutics
2014;(2):139-140
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the Helicobacter pylori (HP) infection in the clinical curative effect of peptic ulcer patients using proton pump inhibitor combined with Clostridium butyricum live bacteria treatment. Methods 112 cases of peptic ulcer patients with Helicobacter pylori infection were randomly divided into two groups, the study group used proton pump inhibitor combined with Clostridium butyricum lactobacillus tablets treatment, the control group only used proton pump inhibitor treatment, the clinical efifcacy of the two groups were compared. Results 1 months after treatment, symptom relief rate in study group was 98.21%, higher than 87.50%in control group, (χ2=4.846, P=0.028);ulcer healing rate in study group was 94.64%, superior than 75%in control group (χ2=8.391, P=0.004);HP eradication rate in study group was 89.29%, higher than 73.21%,in control group (χ2=4.747, P=0.029);adverse medication in the process were nausea, vomiting, loss of appetite, anorexia, dizziness, weakness, abdominal pain and distension, there were no signiifcant differences between two groups. Conclusion Proton pump inhibitor combined with Clostridium butyricum lactobacillus tablets has good curative effect and highly HP eradication rate on treatment with HP type peptic ulcer patients.
