Clinical analysis and treatment of 14 multiple myeloma patients with extramedullary plasmacytoma
10.3969/j.issn.1000-8179.20131259
- VernacularTitle:14例髓外浆细胞瘤患者的临床特征分析及治疗
- Author:
Jing WANG
;
Hongmei JING
;
Min LI
;
Fei DONG
;
Yuping CHEN
;
Xiaoyan KE
- Publication Type:Journal Article
- Keywords:
multiple myeloma;
extramedullary plasmacytoma;
multiple extramedullary plasmacytoma
- From:
Chinese Journal of Clinical Oncology
2014;(10):639-642
- CountryChina
- Language:Chinese
-
Abstract:
Objective: This study aimed to investigate the clinical characteristics, treatment options, and prognosis of multiple myeloma (MM) patients complicated with extramedullary plasmacytoma (EMP). Methods:The case of MM concurrent with EMP are rare. During the period between June 2005 and June 2013, clinical experience, diagnosis, and treatment of MM with EMP cases were retrospectively analyzed. Results:Fourteen cases were diagnosed with MM complicated with EMP in the Third Hospital of Peking Uni-versity, Beijing, China. Among these 14 cases, seven were males and seven were females. The mean age of patients was 56.9 years (ranging from 40 to 80 years old). Nine of the cases were diagnosed with EMP during the preliminary diagnosis, and the remaining five cases developed EMP during the course of treatment. Among the 14 cases, six were solitary EMPs and eight were multiple EMPs. Among the multiple EMP cases, five died, one showed disease progression, and two demonstrated partial regression. Conclusion:The prognosis of MM complicated with EMP is poor. Thus, new treatment strategies should be further explored.
