Determination of Deoxynivalenol in Four Traditional Chinese Herbal Medicines by LC-MS-MS
- VernacularTitle:LC-MS-MS法测定4种中药中的呕吐毒素
- Author:
Dan MAO
;
Su ZHANG
;
Ke CHEN
;
Xiuhong MAO
;
Shen JI
- Publication Type:Journal Article
- Keywords:
Traditional Chinese herbal medicines;
Deoxynivalenol;
LC-MS-MS;
Semen Ziziphi Spinosae;
Semen Sojae Praepara-tum;
Semen Coicis;
Fructus Psoraleae;
Malt Fructus
- From:
China Pharmacist
2014;(4):578-581
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To develop a method for determining deoxynivalenol in four kinds of traditional Chinese herbal medicines. Methods:After being extracted by water, purified by an immunoaffinity column, deoxynivalenol was analyzed by LC-MS-MS. Results:The calibration curve was linear within the range of 2-50 ng·ml-1 for deoxynivalenol. The recovery was 68. 7%-88. 3%. Conclusion:The method is simple, sensitive and accurate in the determination of deoxynivalenol in Semen Ziziphi Spinosae, Semen Sojae Praepara-tum, Semen Coicis and Fructus Psoraleae.
