Quality Standards for Zhichuang Capsules
- VernacularTitle:痔疮胶囊质量标准的建立
- Author:
Ming YUAN
;
Yang XIANG
;
Linshuang XIA
;
Li ZHAI
;
Hang YANG
;
Peng CHEN
- Publication Type:Journal Article
- Keywords:
Zhichuang capsules;
Emodin;
Chrysophanol;
TLC;
HPLC
- From:
China Pharmacist
2014;(4):585-588
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish the quality standards for Zhichuang capsules. Methods: Rhubarb, Mahonia, Angelica and Borneol in the formula were identified by TLC, the content of emodin and chrysophanol from Rhubarb in Zhichuang capsules were deter-mined by HPLC. Results: The qualitative identification was easy to operate with good specificity. The linearity was good ( r =0. 999 9) within the range of 25.8-516.0ng and the average recovery was 97.31%(RSD=0.69%,n=6)for emodin, the linearity was good (r=1.000 0) within the range of 51.1-1 022.0ng and the average recovery was 97.63%(RSD=0.72%,n=6)for Chry-sophanol. Conclusion:The method is reliable and accurate, which can be applied as a quality control method of Zhichuang capsules.
