Comparison of the hemostatic efficacy of pituitrin and oxytocin applying in muscle intramural laparoscopic u-terine myomectomy
10.3760/cma.j.issn.1008-6706.2014.05.009
- VernacularTitle:腹腔镜肌壁间子宫肌瘤剔除术应用垂体后叶素及缩宫素止血的疗效比较
- Author:
Min WEI
- Publication Type:Journal Article
- Keywords:
Laparoscopic;
Uterine myomectomy;
Pituitrin;
Oxytocin;
Comparison of the clinical effect
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;(5):660-662
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare and analyze the clinical curative effect of pituitrin and oxytocin applying in laparoscopic uterine myomectomy intraoperation .Methods According to surgical hemostasis method ,68 patients with uterine fibroids were divided into pituitrin group (group A) and oxytocin group(group B).The surgery time,intr-aoperative blood loss ,the change of postoperative hemoglobin levels and the change of blood pressure before and after treatment were observed.Results In A group,the operative time was (69.8 ±18.0)min,blood loss was (68.3 ± 19.1)mL,postoperative discharge time was (15.2 ±7.8)h,preoperative and postoperative hemoglobin difference val-ue was (10.4 ±2.6) g/L,which were significantly better than those in group B [(82.8 ±17.6) min,(88.5 ± 25.6)mL,(19.4 ±5.9)h,(13.5 ±2.9)g/L],the differences were statistically significant (all P<0.05).Postopera-tive morbidity rate in group A was 5 cases,that in group B was 9 cases,the difference was not statistically significant (P>0.05).In A group,the systolic blood pressure was (152.0 ±8.5)mmHg after treatment for 15min,which was significantly higher than (132.5 ±10.2)mmHg in group B,the difference was statistically significant (P<0.05). There were no statistically significant differences in the systolic blood pressure after treatment for 30min and 45min, and the diastolic blood pressure before and after treatment (all P>0.05).Conclusion Application of pituitrin in laparoscopic surgical hemostasis for patients with uterine fibroids can effectively reduce the surgery time ,decrease the blood loss ,its surgical hemostasis effect is better than oxytocin ,which is worth further clinical application .
