The clinical value of detecting the content of IgA in blood recipients before transfusion

VernacularTitle:受血者输血前检测 IgA 含量的临床价值
Author: Xiuli YANG
Publication Type:Journal Article
Keywords: Recipients; Detection of IgA; Clinical value
From: Chinese Journal of Primary Medicine and Pharmacy 2014;(5):675-676
CountryChina
Language:Chinese
Abstract: Objective To study the clinical application value of detection of IgA content in blood recipients before transfusion .Methods 300 blood recipients were selected as the research subjects ,and the content of IgA was detected before blood transfusion .Results Through the analysis of 300 blood recipients,IgA content of 5 cases was lower than the normal reference value ,the incidence rate of IgA deficiency or low was 1.7%;the IgA content of other 295 cases was in the normal reference value ,the normal rate of IgA was 98.3%.5 blood recipients with IgA deficiency or low were associated with hypersensitivity reactions ,the incidence rate was 100%.Of 295 cases with normal content of IgA,2 cases associated with hypersensitivity reactions ,the incidence rate was 0.7%,the difference between the two groups was statistically significant (χ2 =7.45,P<0.05).Conclusion Determination of IgA content in blood recipi-ents before blood transfusion can effectively guide the correct transfusion ,reduce and prevent the occurrence of hyper-sensitivity reactions of transfusion ,improve the safety of blood transfusion ,which has important application value in clinical practice .