Evaluation of the intensity modulated radiotherapy in early stage cervical cancer with vaginal stump recurrence after surgery
10.3760/cma.j.issn.1006-9801.2014.04.007
- VernacularTitle:调强放疗在早期子宫颈癌术后阴道残端复发治疗中的价值
- Author:
Hua JIN
;
Xiangyu MA
;
Lijing ZHOU
;
Youxiang HOU
;
Weijun YE
- Publication Type:Journal Article
- Keywords:
Uterine cervical neoplasms;
Recurrence;
Radiotherapy,intensity-modulated;
Adverse effects
- From:
Cancer Research and Clinic
2014;26(4):238-240
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of the intensity modulated radiotherapy in early stage cervical cancer with vaginal stump recurrence after surgery.Methods A retrospective concurrent comparative study included 60 patients with vaginal recurrence after surgery in early stage cervical cancer.30 cases of the experimental group were treated with intensity-modulated radiotherapy (IMRT),and 30 cases of the control group were treated with conventional radiotherapy.The efficacy and complications between two groups were compared after 3 treatment cycles.Results Of 30 patients in experimental group,22 patients achieved complete remission,7 had partial and 1 progressed.But in the control group,14 had complete remission,5 reached partial remission,7 were stable and 4 progressed.The effective rates were 96.67 ％ (29/30) and 63.33 ％ (19/30),respectively,in the experimental and control group,which showed statistical significance (P =0.009).In the experimental group,there were 1 case with grade 1 radiation cystitis and 1 case with grade 1 radiation proctitis.In the control group,there were 3 cases of vaginal-rectal fistula,1 case of grade 3 radiation proctitis,2 cases of grade 2 radiation cystitis and 2 cases of grade 1 radiation proctitis.Conclusions IMRT for treating vaginal recurrence of early cervical cancer achieves satisfactory short-term effect.In comparison with conventional radiotherapy,IMRT has higher efficacy but less side effects.
