Research progress of neoadjuvant radiotherapy and prediction of radiosensitivity for rectal cancer
10.3760/cma.j.issn.1006-9801.2014.03.023
- VernacularTitle:直肠癌新辅助放疗及其敏感性预测的研究进展
- Author:
Jun TIAN
- Publication Type:Journal Article
- Keywords:
Rectal neoplasms;
Neoadjuvant radiotherapy;
Radiosensitivity;
Molecular markers;
Gene expression profiling;
Gene chips
- From:
Cancer Research and Clinic
2014;26(3):212-215
- CountryChina
- Language:Chinese
-
Abstract:
Neoadjuvant radiotherapy could decrease the local recurrence rate,increase the probability of the anal sphincter preservation,improve survival rate and the quality of patients' lives.For stage Ⅲpatients with rectal cancer,the recurrence rate is higher in short-course radiotherapy compared with conventionally radiotherapy.Molecular markers combined with gene technology can be used as radiosensitivity indicators.Conventional radiotherapy has a definite effect and radiotherapy combined with chemotherapy has better efficacy.The extensive researches of diverse molecular markers,gene expression profiling and gene chips for rectal cancer provide the basis of personalized treatment.
