Interpretation of major changes in CLSI M100-S24
10.3760/cma.j.issn.1009-9158.2014.04.005
- VernacularTitle:2014年CLSI M100-S24主要更新内容解读
- Author:
Yawei ZHANG
;
Hui WANG
- Publication Type:Journal Article
- Keywords:
Anti-bacterial agents;
Microbial sensitivity tests;
Enterobacteriaceae
- From:
Chinese Journal of Laboratory Medicine
2014;37(4):256-260
- CountryChina
- Language:Chinese
-
Abstract:
Individualized therapy is dependent on rapid and accurate diagnosis of pathogens,and refined susceptibility reporting.The annually revised interpretive criteria of Clinical and Laboratory Standards Institute (CLSI) causes widespread concern of microbiologists.The major changes in CLSI M100-S24 are described in this article.The document mainly changed the Cefepime breakpoint for Enterobacteriaceae and introduced a new concept-- susceptible-dose dependent interpretive category.Optimizing the use of antimicrobial agents requires clinical microbiologists and clinicians to have a good knowledge of the new breakpoints.