Effects of extracorporeal membrane oxygenation on coagulation during lung transplantation
10.3760/cma.j.issn.0254-1785.2014.04.008
- VernacularTitle:应用体外膜肺氧合对肺移植受者围手术期凝血功能的影响
- Author:
Xingfeng ZHU
;
Jingyu CHEN
;
Mingfeng ZHENG
;
Yijun HE
;
Shugao YE
;
Feng LIU
- Publication Type:Journal Article
- Keywords:
Extracorporeal membrane oxygenation;
Lung transplantation;
Coagulation
- From:
Chinese Journal of Organ Transplantation
2014;35(4):225-227
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of extracorporeal membrane oxygenation (ECMO) on coagulation during lung trangplantation.Method Forty cases of end stage lung diseases received bilateral sequential single lung transplantation during July 2007 and Mar.2012.The patients were divided into two groups in terms of ECMO.ECMO was applied before lung transplantation if needed.The amount of bleeding during surgery was recorded.The venous blood samples were collected during and after operation for the measurements of the following parameters:activated whole blood clot time (ACT),prothrombin time (PT),activated partial thromboplastin time (APTT),thrombin time (TT) and plasma fibrinogen (Fg).Result The coagulation and the amount of bleeding showed no significant difference between the two groups.Wound infection occurred in 2 patients where the ECMO tube was inserted and femoral arterial thrombosis in one patient.All of the three patients were cured and discharged.Conclusion ECMO didn't cause excessive bleeding or coagulation dysfunction during lung transplantation,yet it maybe increase the occurrence of local thrombosis.
