Changes of serum enzymes in acute mesenteric vasculopathy
10.3760/cma.j.issn.1007-631X.2014.04.012
- VernacularTitle:急性肠系膜血管病变时的血清酶谱变化
- Author:
Lu HU
;
Fuxian ZHANG
- Publication Type:Journal Article
- Keywords:
Mesenteric vascular occlusion;
Disease models,animal;
Enzymes;
Early diagnosis
- From:
Chinese Journal of General Surgery
2014;29(4):285-288
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study changes of serum enzymes among acute mesenteric vasculopathy (AMV) and several surgical acute abdomens for early diagnosis of acute mesenteric vasculopathy.Methods Rabbit models were established for acute mesenteric artery ischemia,acute mesenteric venous ischemia,acute mechanical ileus,acute strangulated intestinal obstruction,acute gastric perforation,acute pancreatitis,sham group,blank control group.Serum enzymes were tested after 0,1,3,6,9 h.Result Compared with blank control,acute mesenteric vasculopathy experienced significantly alterations of the serum enzymes.ALT (alanine aminotransferase),ALP (alkaline phosphatase),r-GT (glutamyl transferthe enzyme) were significantly higher after mesenteric veins blocked 3 hours,LDH (lactate dehydrogenase) was significantly higher after mesenteric venous blocked 6 hours (P ＜ 0.05).ALT was significantly higher after mesenteric artery blocked 6 hours (P ＜ 0.05).Elevated ALT were statistically different in acute mesenteric vasculopathy compared with blank control,sham group,gastric perforation,mechanical ileus,and strangulated intestinal obstruction (all P ＜ 0.05) ; r-GT level was statistically different between acute mesenteric artery ischemia and acute mesenteric venous ischemia.Conclusions Mesurements of serum enzymes level are helpful to make early diagnosis of acute mesenteric vasculopathy.
