Relationship and the underlying mechanism of cholesterol metabolism with colorectal cancer
10.3760/cma.j.issn.1000-6699.2014.03.020
- VernacularTitle:胆固醇代谢与结直肠癌的关系及其机制
- Author:
Yongtao YANG
;
Hua SHENG
;
Zhiwen LI
;
Rongquan WANG
- Publication Type:Journal Article
- Keywords:
Cholesterol;
Colorectal cancer;
Bile acids;
Statins
- From:
Chinese Journal of Endocrinology and Metabolism
2014;30(3):254-257
- CountryChina
- Language:Chinese
-
Abstract:
Recent meta-analysis based on both clinical trials and epidemiological studies has revealed the relationship of dietary cholesterol,blood cholesterol level and cholesterol lowering drugs (statins) with colorectal cancer.This review summarises the advances in current evidences of linking cholesterol metabolism and risk of colorectal cancer and the underlying molecular mechanisms based on pharmacogenetics and molecular pathology.
