Malnutrition in early life and risk of type 2 diabetes
10.3760/cma.j.issn.1000-6699.2014.03.018
- VernacularTitle:生命早期营养不良与2型糖尿病
- Author:
Mingling CHEN
;
Hong FANG
;
Wanghong XU
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Malnutrition;
Low birth weight;
Early life
- From:
Chinese Journal of Endocrinology and Metabolism
2014;30(3):247-249
- CountryChina
- Language:Chinese
-
Abstract:
Factors in uterus may be important in the aetiology of type 2 diabetes.Malnutrition during early life can affect insulin secretion and result in insulin resistance,and such effects are markedly exaggerated when facing over-nutrition in later life.This paper gives a review about the population evidence and epigenetic mechanism in the generational susceptibility to type 2 diabetes.