Relationship of subclinical hypothyroidism with metabolic syndrome and its components
10.3760/cma.j.issn.1000-6699.2014.03.009
- VernacularTitle:亚临床甲状腺功能减退与代谢综合征及其组分的关系
- Author:
Xiaoling GAN
;
Qingyu CHEN
;
Jinwu CHEN
;
Bei LIAO
;
Yan LI
- Publication Type:Journal Article
- Keywords:
Subclinical hypothyroidism;
Metabolic syndrome
- From:
Chinese Journal of Endocrinology and Metabolism
2014;30(3):213-215
- CountryChina
- Language:Chinese
-
Abstract:
The relationship between subclinical hypothyroidism (SCH) and the components of metabolic syndrome (MS) was explored.A total of 2 252 subjects aged 20 to 79 years from medical examination were identified.The prevalence of SCH was 4.88%.The rate of 7.30% in female was markedly higher than 2.17% in male(P<0.01).The highest SCH prevalence in adults was in the ≥70 years old group.The prevalence of SCH in female was increased with age(P<0.01).Compared with the euthyroid group,body mass index,triglyceride,and low density lipoprotein-cholesterol were significantly elevated (P<0.05),while high density lipoprotein-cholesterol was significantly decreased in SCH group(P<0.05).The incidences of hypertension,dyslipidosis,and MS in SCH group were significantly higher than those in euthyroid group(P<0.05 or P<0.01) ; Serum TSH in the MS group was higher than that in the Non-MS group[(2.43 ± 1.55 vs 2.21 ± 1.48) mU/L,P<0.01].The incidence of SCH in MS group was significantly higher than that in the Non-MS group (7.69% vs 4.25%,P<0.05).The prevalence of SCH in women was increased with age.Multiple factors of dysbolism were clustered in subjects with SCH.There is a correlation between SCH and MS.