Study on Extraction Technology of Hegan Lidan Granules
- VernacularTitle:和肝利胆颗粒提取工艺研究
- Author:
Bei HU
;
Hongda MA
;
Xuehui SUN
;
Jin ZHANG
;
Guobing SHI
- Publication Type:Journal Article
- Keywords:
Hegan Lidan granules;
Baicalin;
Orthogonal design;
HPLC
- From:
China Pharmacist
2014;(4):565-567
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To optimize the extraction process of Hegan Lidan granules. Methods:In order to choose the optimal tech-nological parameters, the content of baicalin was determined by HPLC. An orthogonal method was utilized with solvent volume, extrac-tion time and extraction times as the impacting factors and the content of baicalin and extraction rate as the indices. Results:The opti-mal parameters were as follows:using 8-fold water as the solvent, the raw material was extracted three times with 2 h for each. Con-clusion:The process is steady and feasible, and can be used in the extraction of Hegan Lidan granules.