Application of functional imaging in diagnosis of diabetes mellitus
10.3760/cma.j.issn.1000-6699.2014.04.021
- VernacularTitle:功能显像在糖尿病诊断中的应用与展望
- Author:
Zhemin HUANG
;
Zhengwei ZHANG
;
Chuantao ZUO
;
Yihui GUAN
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Functional imaging;
β cell mass;
Glucose transporters
- From:
Chinese Journal of Endocrinology and Metabolism
2014;30(4):357-359
- CountryChina
- Language:Chinese
-
Abstract:
In either type 1 or type 2 diabetes,there is significant loss of β cell mass.Understanding the changing of β cell mass in the course of diabetes would provide important information for diagnosis and treatment.Functional imaging like magnetic resonance imaging or positron emission tomography (PET) can provide safe and noninvasive detection of loss of β cell mass in the course of diabetes.Among them,radio-labelled imaging is the most sensitive imaging procedure of the β cell ; For dihydrotetrabenazine PET imaging aiming β cell mass,there has been some primary outcome.For the key factor causing type 2 diabetes,18 F-6-deoxy-6-fluoro-D-glucose (18F-6-FDG) PET imaging is an effective tracer to study the glucose transporting condition in vivo.Further development of functional imaging will be of great value in diagnosis and treatment of diabetes.
