Effects of sevoflurane anesthesia on left ventricular function in young infants
10.3760/cma.j.issn.0254-1416.2014.01.003
- VernacularTitle:七氟醚麻醉对低龄婴儿左心功能的影响
- Author:
Zhen SUN
;
Changguo PENG
;
Jing LYU
;
Fuzhi PAN
;
Wei QIAO
;
Weidong REN
- Publication Type:Journal Article
- Keywords:
Anesthetics,inhalation;
Infant,newborn;
Heart function tests
- From:
Chinese Journal of Anesthesiology
2014;34(1):9-11
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of sevoflurane anesthesia on the left ventricular function in young infants.Methods Sixteen ASA physical status Ⅰ pediatric patients,aged 28-75 days,weighing 4.0-6.1 kg,undergoing elective resection of hemangioma on the body surface under general anesthesia with sevoflurane were studied.After the pediatric patients inhaled 6 ％ sevoflurane for 4 min,tracheal intubation was performed,and the pediatric patients were mechanically ventilated.Anesthesia was maintained with sevoflurane with the endtidal concentration of 4.48％-5.12％.Transthoracic echocardiographic examinations were performed before induction of anesthesia (baseline,T0),immediately before intubation (T1),at 10 and 30 min after intubation (T2,3),and at 20 min and 1 h after extubation (T4,5) to calculate Tei index.Results Compared with the baseline value at T0,Tei index was significantly increased at T1-4 (P ＜ 0.05 or 0.01),and no significant change was found in Tei index at T5 (P ＞ 0.05).The blood pressure and heart rate were stable and no adverse cardiovascular events were found during surgery.Conclusion Although sevoflurane anesthesia does not induce cardiovascular events,it decreases the left ventricular function to some extent in young infants.
