Effcacy of Amiodarone on acute myocardial infarction and atrial fibrillation in elderly patients

VernacularTitle:胺碘酮对急性心肌梗死老年患者合并心房颤动的疗效分析
Author: Xinwen HUANG ; Jinpeng WANG ; Hailin LI
Publication Type:Journal Article
Keywords: Myocardial infarction; Atrial fibrillation; Amiodarone
From: Chinese Journal of Geriatrics 2014;33(5):460-461
CountryChina
Language:Chinese
Abstract: Objective To investigate the the effect of Amiodaroneo on acute myocardial infarction (AMI) and atrial fibrillation (AF) in elderly patients,and provide the basis for the treatment.Methods A total of 108 patients with AMI and AF in our hospital from January 2009 to June 2013 were collected and randomly divided into control and experimental groups,each group of 54 cases.The control group was treated with cedilanid and the experimental group were treated with amiodarone.AF control rate,sinus rhythm maintenance rate and adverse reactions of the two groups were analyzed and compared after treatment.Results The AF control rate of experimental group was significantly higher than that of control group in 6 h,12 h,24 h and 48 h after treatment (x2=5.173,5.066,4.757,6.684,P＜0.05).Sinus rhythm maintenance rate of experimental group was increased compared with control group (47 cases vs.24 cases,x2=21.748,P＜0.01).Adverse reaction rates of the experimental group was lower than the control group (x2 =15.621,P＜0.01).Conclusions The treatment of AMI and AF by amiodarone is betterr and safe than cedilanid alone,so it is worth popularizing and applying on clinic.