Two Cases of Primary Cutaneous Marginal Zone B-cell Lymphoma.
- Author:
Kyu yeop LEE
1
;
Eun Chun HAN
;
Do Young KIM
;
Kee Yang CHUNG
Author Information
1. Department of Dermatology and Cutaneous Biology Research Institute,Yonsei University College of Medicine, Seoul, Korea. derma@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
MALT lymphoma;
Marginal zone B-cell lymphoma
- MeSH:
Adult;
B-Lymphocytes;
Biopsy;
Bone Marrow;
Female;
Follow-Up Studies;
Humans;
Lymphocytes;
Lymphoid Tissue;
Lymphoma;
Lymphoma, B-Cell;
Lymphoma, B-Cell, Marginal Zone;
Lymphoma, Non-Hodgkin;
Middle Aged;
Neoplasm Metastasis;
Nose;
Prognosis;
Recurrence;
Skin
- From:Korean Journal of Dermatology
2008;46(5):710-714
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary cutaneous marginal zone B-cell lymphoma, known as the cutaneous counterpart of mucosa-associated lymphatic tissue lymphoma (MALT lymphoma), is the most frequent of the primary cutaneous B-cell lymphoma. It is one of the low-grade lymphomas of B-cell type, which has an excellent prognosis with indolent behavior, despite frequent cutaneous recurrences. Histologically, cutaneous marginal zone B-cell lymphoma is composed of polymorphous infiltrate that includes centrocyte-like, centroblast-like, monocytoid, and lymphoplasmacytoid lymphocytes. We present two cases of primary cutaneous marginal zone B-cell lymphoma. A 48-year-old woman visited the dermatologic clinic with 1.5x1.5 cm sized, skin colored, palpable nodule on the left temporal area and a 26-year-old man visited the dermatologic clinic with 1x1 cm sized erythematous nodule on the nose. Both of them showed compatible histologic findings of marginal zone B-cell lymphoma and had no past medical history and no evidence of metastasis on PET-CT and bone marrow biopsy. The woman was treated with radiation treatment after excision and the man was treated with radiation treatment alone. Follow-up indicates that 1 year after treatment there is no evidence of recurrence.
