Preliminary clinical research on the afterloading brachytherapy inverse intensity-modulated radiotherapy of gynecological tumor
10.3760/cma.j.issn.0254-5098.2014.04.012
- VernacularTitle:妇科肿瘤后装逆向调强放疗的初步临床研究
- Author:
Qianxi NI
;
Dihong TANG
;
Jiutang ZHANG
- Publication Type:Journal Article
- Keywords:
Gynecologic tumor;
Inverse planning simulated annealing(IPSA);
Dosimetry;
Organs at risk;
Radioactive complications
- From:
Chinese Journal of Radiological Medicine and Protection
2014;34(4):286-288
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical value of the afterloading brachytherapy inverse intensity-modulated radiotherapy of gynecological tumor.Methods Twenty patients with cervical cancer,were randomly divided into A and B groups,10 cases for each group.Group A received the afterloading brachytherapy inverse intensity-modulated radiotherapy.Group B received the three-dimensional comformal afterloading brachytherapy.The target volume dose distribution,organs at risk (rectum,bladder),shortterm curative effect and radioactive complications were analyzed on both groups.Results The dose homogeneity index of the target volume of group A was 52.43-± 0.45,better than that of group B (46.37 ± 1.45) (t =0.92,P ＜ 0.05).The maximum dose of rectum and bladder of group A were about 37％,35％,less than that of group B (t =1.34,1.39,P ＜ 0.05).The 75％ prescription dose irradiated volume of rectum and bladder of group A were about only 1/2 of group B (t =1.23,1.13,P ＜ 0.05).The local control rate of 96％ for group A was better than 93％ for group B (t =1.25,P ＜ 0.05).Conclusions Afterloading brachytherapy inverse intensity-modulated radiotherapy technique could be better than the three-dimensional comformal afterloading brachytherapy.It should be recommended for gynecological tumor.
