Effects of batroxobin on blood coagulation and fibrinolytic function of patients with sudden deafness
10.3969/j.issn.1673-4130.2014.10.015
- VernacularTitle:巴曲酶对突发性耳聋患者凝血及纤维蛋白溶解功能的影响
- Author:
Gangqiang WANG
;
Shanluan ZHENG
- Publication Type:Journal Article
- Keywords:
batroxobin;
hearing loss;
fibrinolysis;
coagulation
- From:
International Journal of Laboratory Medicine
2014;(10):1268-1269
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of batroxobin on blood coagulation and fibrinolytic function of patients with sud-den deafness .Methods 87 patients with sudden deafness were enrolled .Their prothrombin time(PT ) ,activated partial thrombo-plastin time(APTT) ,thrombin time(TT) ,fibrinogen(Fib) ,D-dimer and fibrin/fibrinogen degradation products(FDP) were detec-ted before batroxobin treatment and 3 ,6 days after treatment .Results Compared with pre-treatment ,patients after treatment expe-rienced prolonged PT and TT (P<0 .05) ,decreased Fib(P<0 .01) ,increased FDP (P<0 .01) ,and the difference of APTT ,D-di-mer between treatment before and after showed no statistically significant (P>0 .05) .Conclusion PT ,TT ,Fib ,FDP can be applied to monitor the coagulation and fibrinolytic function of patients with sudden deafness treated with batroxobin .
