Advances in Study on Bile Reflux Gastritis
10.3969/j.issn.1008-7125.2014.05.013
- VernacularTitle:胆汁反流性胃炎研究进展
- Author:
Ying WEI
;
Shigang DING
- Publication Type:Journal Article
- Keywords:
Bile Reflux Gastritis;
Duodenogastric Reflux;
Bile Acids and Salts;
Diagnosis;
Therapy
- From:Chinese Journal of Gastroenterology
2014;(5):305-308
- CountryChina
- Language:Chinese
-
Abstract:
Bile reflux gastritis (BRG)has been recognized as a chemical gastropathy due to excessive duodenogastric reflux (DGR).Abnormalities in pyloric anatomic structure,as well as antropyloric and duodenal dysmotility are considered to be implicated in the occurrence of pathologic DGR.Bile acid may induce apoptosis of gastric mucosal cells,and high concentration of bile acid plays a crucial role in the induction of intestinal metaplasia in stomach.In this review article, advances in study on BRG,including the mechanisms of DGR,the pathogenic effect of bile acid on gastric mucosa,and the diagnosis and treatment of BRG were summarized.
