Bilateral stereotactic radiofrequency amygdalohippocampectomy for the treatment of bilateral medial temporal lobe epilepsy
10.3969/j.issn.1006-5725.2014.06.006
- VernacularTitle:立体定向双侧海马杏仁核复合体毁损术治疗双颞叶内侧型癫痫
- Author:
Quanjun ZHAO
;
Huimin LUO
;
Zengmin TIANA
;
Zhaohui WU
;
Fuli WANG
;
Feng YIN
;
Hulin ZHAO
;
Haiying WANG
- Publication Type:Journal Article
- Keywords:
Bilateral medial temporal lobe epilepsy;
Stereotactic radiofrequency amygdalohippocampec-tomy;
Neuropsychology;
Seizure severity
- From:
The Journal of Practical Medicine
2014;(6):853-856
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively analyze the effect and safety of bilateral stereotactic radiofrequency amygdalohippocampectomy (SAHE) for treatment of bilateral medial temporal lobe epilepsy (BMTLE). Methods Twelve BMTLE patients were treated with bilateral SAHE under limited coagulations. Clinical parameters were evaluated with the programs of Engel′s classification, Liverpool Seizure Severity Scale (LSSS) 2.0, Wechsler Adult Intelligence Scale-Revised (WAIS-R) and Wechsler Memory Scale-Revised (WMS-R), respectively. Results Five patients (42%) were assessed as EngelⅠwith 12 ~ 62-month follow-up. Seizure severity scores were declined sharply compared with the baseline of the patients with out seizure free. Function of memory and intelligence was transiently declined without statistical significance immediately after operation (P >0.05), but was significantly increasedat 6 months after operation (P < 0.05). Conclusion Bilateral SAHE could terminate seizures or reduce seizure severity in patients with BMTLE. Under the circumstance of limited coagulations, neuropsychological function was improved along with seizure control.
