Influencing factors of perioperative myocardial injury in patients undergone percutaneous coronary intervention
10.3969/j.issn.1006-5725.2014.05.023
- VernacularTitle:经皮冠脉介入治疗围手术期心肌损伤影响因素分析
- Author:
Jianlong SHENG
;
Xiaochen WANG
;
Banglong XU
;
Jixiong WU
;
Zhangle HU
- Publication Type:Journal Article
- Keywords:
Angioplasty,transluminal,percutaneous coronary;
Perioperative myocardial injury;
Rosuvastatin;
High-sensitivity troponin
- From:
The Journal of Practical Medicine
2014;(5):748-751
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate influencing factors of perioperative myocardial injury in patients undergone percutaneous coronary intervention (PCI). Methods Ninty one patients with coronary heart disease (including stable angina and unstable angina) underwent PCI, the perioperative myocardial injury incidence were observed prospectively by monitoring the preoperative and postoperative high sensitivity troponin protein levels to investigate the influencing factors of perioperative myocardial injury by Logistic regression analysis. Results There were no statistically significance in perioperative myocardial injury incidence (62.5%vs 68.7%, P=0.618) and perioperative myocardial infarction incidence (29.2%vs 20.9%, P=0.411) between stable angina and unstable angina groups . These factors of perioperative myocardial injury in patients undergone PCI by Logistic regression analysis were analysed, and we found that the influencing factors were the application loading dose rosuvastatin before PCI, preoperative statin therapy more than one month, apolipoprotein A levels and total stent length. Conclusion Application loading dose of rosuvastatin before PCI, preoperative statin therapy more than one month, apolipoprotein A levels are related to perioperative myocardial injury reduction, whereas the total length of the stent is associated with an increased occurrence of perioperative myocardial injury.
