Clinical study of functional hemispherectomy for pediatric intractable epilepsy with hemisphere lesions
10.3969/j.issn.1006-5725.2014.06.007
- VernacularTitle:功能性大脑半球切除术治疗儿童半球病变致难治性癫痫24例
- Author:
Xu CHEN
;
Hang HU
;
Lidong CHENG
;
Wei JIANG
;
Kai SHU
;
Ting LEI
;
Ling LI
- Publication Type:Journal Article
- Keywords:
Intractable Epilepsy;
Functional hemispherectomy;
Hemispheric lesions;
Presurgical evaluation;
Pediatric
- From:
The Journal of Practical Medicine
2014;(6):857-860
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the results of functional hemispherectomy for pediatric intractable epilepsy with hemisphere lesions , and to explore the indications of functional hemispherectomy , as well as the prognosis. Methods Twenty-four children with intractable epilepsy caused by hemisphere lesions were included , who underwent functional hemispherectomy. All patients were followed up for 3 ~ 48 months. Results All 24 cases obtained improvement of abnormal behavior , and no significant exacerbation of neurological deficits was observed. During the follow-up, 18 cases were in EngelⅠ(75%), 5 in Engel Ⅱ(21%), and 1 in Engel Ⅰ(4%) respectively. No long-term complication was observed. Conclusion Comprehensive presurgical evaluation is a prerequisite for the surgical treatment of pediatric intractable epilepsy caused by hemisphere lesions. Functional hemispherectomy can effectively control seizures and obviously improve the prognosis.
