Clinical analysis of intestinal neuroendocrine tumors
10.3969/j.issn.1000-8179.20132053
- VernacularTitle:肠道神经内分泌肿瘤临床分析
- Author:
Guangyu YAO
;
Yi BA
- Publication Type:Journal Article
- Keywords:
intestinal tract;
neuroendocrine tumors;
clinico-pathological features;
metastasis
- From:
Chinese Journal of Clinical Oncology
2014;(8):522-525
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinico-pathological features of intestinal neuroendocrine tumors (NET), as well as the treat-ment protocols and survival of intestinal NET patients. Methods:Clinico-pathological features of 82 intestinal NET patients were retro-spectively reviewed. Results:The male to female ratio was 1.41:1 in the group of patients, and the mean age was 48.72 ± 13.26. Up to 72 cases were NET, 7 were neuroendocrine cancer, and 3 were mixed adeno-neuroendocrine carcinoma. The most commonly observed organ exhibiting primary lesion of the tumors was the rectum. The overall five-year survival rates were 78%and 80%among all the pa-tients and among the NET patients, respectively. Tumors of different histological types demonstrated statistically significant differences in terms of primary site, pT stage, and metastasis (P<0.05). The pT stage, histological classification, age, and primary site of the tumors were associated with the metastasis of the intestinal NETs (P<0.05). Age was the main risk factor of metastasis in the tumors. Conclu-sions:Intestinal neuroendocrine neoplasms usually occur in males, and the most commonly involved organ is the rectum. Age is an im-portant factor of neuroendocrine tumor metastasis.
